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After a volcano erupts on the popular island resort Santa Marta, a bizarre new ecosystem is created from the irradiated lava. While Randy and Nick fought mutant carnivorous plants (homage to Biollante), Monique and Craven find a beehive of giant mutant bees. The whole team is then attacked by the giant bees while Zilla Junior battles the queen bee in the heart of the volcano. Zilla Junior was able to destroy the hive, and kill the queen bee. However, the queen reappeared when an alien race tried to invade the Earth, during the Monster Wars arc. It was sent to aide El Gusano Gigante in invading Moscow. However, it was killed when the aliens lost control of the mutations, and they became a threat.
The way the ecosystem is created in her first appearance, resembles the one from the 1957 movie The Black Scorpion